Thymosin Alpha-1
Thymosin Alpha-1 (TA-1) is a 28-amino-acid immunomodulatory peptide naturally produced by the thymus gland. It enhances and restores immune function by promoting T-cell maturation, boosting NK cell cytotoxicity, and balancing cytokine signaling. Unlike immune stimulants, it promotes homeostasis — increasing immune vigilance while calming overactivation. Used for decades in immunocompromised patients. Available as lyophilized powder with ≥98% purity.
Available SKUs
| Model | Specification | MOQ |
|---|---|---|
| ta1-5 | 5ml | 1 vial |
| ta1-10 | 10ml | 1 vial |
| ta1-20 | 20ml | 1 vial |
Product Overview
First characterized by Dr. Allan L. Goldstein in 1972, Thymosin Alpha-1 primarily influences T-cell production and activity. It enhances both adaptive (T-cell-driven) and innate (first-line defense) immunity while promoting homeostasis rather than immune overdrive. Used clinically for decades to support patients with chronic infections, cancer, and viral illnesses, it is now gaining popularity among high-performance individuals and longevity-focused users.
Mechanism of Action
TA-1 promotes maturation and differentiation of CD4+ helper and CD8+ cytotoxic T-cells. It enhances NK cell cytotoxicity for early threat elimination. It balances inflammatory response by increasing IL-2 and IFN-γ while suppressing excessive IL-6 and TNF-α — immunomodulatory rather than immunosuppressive.
Key Benefits
Immune Modulation — Maintains balance between overactive and underactive immune systems. Enhances T-cell function and NK cell activity without broad immune suppression.
Chronic Inflammation Reduction — Minimizes long-term damage from persistent inflammation by recalibrating immune functionality. Improves symptoms and reduces flare-ups in autoimmune conditions.
Infection Defense — Strengthens defense against viral, bacterial, and fungal infections in immunocompromised individuals. Supports recovery from illness and intense physical stress.
Autoimmune Recovery — Encourages the immune system to distinguish self from non-self more accurately, halting disease progression while alleviating fatigue, joint pain, and cognitive impairment.
References
- Romani L, et al. Thymosin α1. *Ann N Y Acad Sci.* 2007;1112(1):326–338.
- Garaci E. Thymosin alpha1: a historical overview. *Ann N Y Acad Sci.* 2007;1112:14–20.
- Rezzani R, et al. Thymus and aging: morphological, radiological, and functional overview. *Age.* 2014;36:313–351.
| CAS Number | 62304-98-7 |
|---|---|
| Molecular Formula | C129H215N33O55 |
| Molecular Weight | 3108.31 g/mol |
| Sequence/Composition | 28 amino acids (thymic peptide) |
| Amino Acids | 28 |
| Form | Lyophilized powder |
| Purity | ≥99% by HPLC |
| Storage | -20°C desiccated |
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