LC120

Product Overview

LC120 is part of the LIPO-C family used in fat-metabolism and energy-conversion studies. It combines amino acid derivatives and nutrient cofactors in a single aqueous solution. L-carnitine serves as the molecular escort for long-chain fatty acids across the inner mitochondrial membrane, while methionine and choline support hepatic lipid export, and dexpanthenol (provitamin B5) aids coenzyme A synthesis.

Mechanism of Action

The primary mechanism centers on the carnitine shuttle: CPT1 enzymes attach fatty acids to carnitine for transport across the inner mitochondrial membrane. Once inside, the fatty acid undergoes beta-oxidation to generate ATP. Methionine and choline support lipid metabolism and liver function, while dexpanthenol contributes to coenzyme A synthesis for energy pathways.

Key Benefits

Mitochondrial Fuel Transport — L-carnitine facilitates transport of long-chain fatty acids into mitochondria, addressing the rate-limiting step in fat burning.

Beta-Oxidation Support — Enhances the rate of fat breakdown into Acetyl-CoA to fuel the Krebs cycle, supporting efficient energy conversion.

Hepatic Lipid Metabolism — Methionine and choline promote liver fat export and support hepatic function.

Precise Liquid Dosing — Sterile liquid formulation allows for precise titration in metabolic research and dose-dependent response studies.

References

1. Stephens FB, et al. New insights concerning the role of carnitine in the regulation of fuel metabolism in skeletal muscle. *J Physiol.* 2007.
2. Ringseis R, et al. The role of carnitine in the regulation of glucose homeostasis and insulin sensitivity. *Eur J Nutr.* 2012.