GHK-Cu (Copper Peptide)

Product Overview

GHK-Cu is a natural copper complex found in human plasma, saliva, and urine. Levels decline by approximately 50% by age 60, correlating with reduced regenerative capacity. As a regenerative peptide, GHK-Cu influences gene expression at a fundamental level, capable of up- and down-regulating more than 4,000 genes, resetting aging cells to more youthful patterns. It stimulates collagen Types I and III, raises elastin and glycosaminoglycan levels, and supports dermal fibroblast function.

Mechanism of Action

GHK-Cu stimulates blood vessel and nerve growth, enhances collagen and elastin production, supports dermal fibroblast function, and promotes healing by influencing cellular function at the genetic level. It resets aging cells to more youthful patterns of gene expression, functioning as a prospective agent for skin inflammation, tissue repair, and wound healing.

Key Benefits

Skin Care & Anti-Aging — Stimulates collagen and elastin production to improve firmness, reduce wrinkles, and enhance skin texture. Studies show collagen production increases by 70% after one month of use. Improves skin density, thickness, and overall radiance.

Tissue Repair & Regeneration — Accelerates wound healing through collagen synthesis at injury sites, promotes angiogenesis for oxygen and nutrient delivery, and regulates inflammation to prevent chronic complications. Supports recovery from injuries, surgical incisions, and burns.

Hair Growth Support — Prolongs the active hair growth phase (anagen), enhances scalp microcirculation, reduces follicular inflammation, and increases follicle size. Promotes thicker, healthier hair strands and reduces shedding, comparable to minoxidil effects.

References

1. Pickart L. The human tri-peptide GHK and tissue remodeling. *J Biomater Sci Polym Ed.* 2008;19:969–988.
2. Meiners S, Eickelberg O. Next-generation personalized drug discovery: the tripeptide GHK hits center stage in COPD. *Genome Med.* 2012;4(8):70.
3. Rakhmetova KK, et al. Effects of Gly-His-Lys-D-Ala peptide on skin wound regeneration. *Bull Exp Biol Med.* 2024;176(3):411–416.